The UK Kawasaki Disease Foundation

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Kawasaki Disease Research Links

We are building what we wish to be the most comprehensive on line research resource relevant to our UK community, for clinicians.  That’s an ambition we’ll keep working towards – adding to the information here as often as possible.

If there are key papers that you think it is important that we have links to, please do contact us and we will add them.  If you are working on research into Kawasaki Disease and want to promote that here – or discuss it with us, please get in touch. ​If you’d like us to post information from your organisation on our website, links to relevant papers or articles, please contact us.

  • Acute management
  • Cardiology
  • Guidelines
  • Kawasaki Disease Incidence
  • Long term clinical care
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All Research Links

The emergence of Kawasaki Disease in India and China

Fuyong Jiao, Ankur Kumar Jindal, Vignesh Pandiarajan, Raju Khubchandani, Nutan Kamath, Tapas Sabui, Rakesh Mondal, Priyankar Pal, and Surjit Singhcorresponding

October 2017

Diagnosis and management of Kawasaki Disease in developing countries

Kawasaki Disease Increases the Incidence of Myopia

Yung-Jen Kung,1 Chang-Ching Wei,2,3 Liuh An Chen,4 Jiin Yi Chen,4 Ching-YaoChang,5 Chao-Jen Lin,6,7 Yun-Ping Lim,8 Peng-Tai Tien,2,9 Hsuan-Ju Chen,10Yong-San Huang,1 Hui-Ju Lin,4,9 and Lei Wan5,9,11,12

July 2017

Patients with Kawasaki Disease exhibited a substantially higher risk for developing myopia according to research in Taiwan.

Management of Kawasaki Disease in adults

Kara J Denby, Daniel E Clark, Larry W Markham

July 2017

This review addresses gaps in the current knowledge of the disease and its optimal treatment, differences in the AHA and JCS guidelines, targets for future research and obstacles to transition of care from adolescence into adulthood.

Corticosteroid therapy in Kawasaki Disease

Carl Galloway, MD, FHM, FAAP Frontline Medical News

July 2017

This study suggests that corticosteroids combined with IVIG as initial therapy for KD showed a more protective effect against CAA, compared with conventional IVIG therapy, and the efficacy was more pronounced in the high-risk patient group.

Dissecting Kawasaki disease: a state-of-the-art review

S. M. Dietz 1 & D. van Stijn1 & D. Burgner2,3,4 & M. Levin5 & I. M. Kuipers 6 & B. A. Hutten7 & T. W. Kuijpers1

June 2017

A discussion paper on Kawasaki Disease which concludes that many aspects of KD remain unknown, although there is growing knowledge on the etiology

Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart

Brian W. McCrindle , Anne H. Rowley , Jane W. Newburger , Jane C. Burns , Anne F. Bolger , Michael Gewitz , Annette L. Baker , Mary Anne Jackson , Masato Takahashi , Pinak B. Shah , Tohru Kobayashi , Mei-Hwan Wu , Tsutomu T. Saji , and Elfriede Pahl and On behalf of the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Surgery and Anesthesia; and Council on Epidemiology and Prevention

March 2017

AHA 2017 recommendations provide updated and best evidence-based guidance to healthcare providers who diagnose and manage Kawasaki disease, but clinical decision making should be individualized to specific patient circumstances.

NIHR Signal Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease

Chen, S.,Dong, Y.,Kiuchi, M. G.,Wang, J.,Li, R.,Ling, Z.,Zhou, T.,Wang, Z.,Martinek, M.,Purerfellner, H.,Liu, S.,Krucoff, M. W.

February 2017

This study suggests that early treatment with corticosteroids on top of standard therapy reduces the risk of serious heart problems in children under five with Kawasaki Disease.

Kawasaki Disease – Pearls and Pitfalls

Dr Katie Knight, with advice kindly given by Dr James Seddon, Paediatric ID Consultant

January 2017

An article on the diagnosis and treatment of Kawasaki Disease.

Coronary Artery Complication in Kawasaki Disease and the Importance of Early Intervention

Shaojie Chen, MD, MM, PhD1,2; Ying Dong, MD, MM, PhD3; Marcio Galindo Kiuchi, MD, MS, PhD4; et al

December 2016

This systematic review and meta-analysis demonstrates that adjunctive corticosteroid therapy was associated with a significantly lower rate of coronary artery complication compared with intravenous immunoglobulin therapy, particularly among high-risk patients.

Coronary Artery Complication in Kawasaki Disease and the Importance of Early Intervention : A Systematic Review and Meta-analysis.

Chen S, Dong Y, Kiuchi MG, Wang J, Li R, Ling Z, Zhou T, Wang Z, Martinek M, Pürerfellner H, Liu S, Krucoff MW.

December 2016

A paper evaluating the effect of corticosteroid therapy in KD.

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Paediatric Care Online is an online decision support system designed for healthcare professionals who see children at the point of care. This innovative tool provides immediate access to clinically assured information to inform decisions and diagnosis. Societi have been working alongside PCO UK to add a new Key Practice Point for ‘persistent fever’ so that, with the help of their online app, Kawasaki Disease will be more easily recognised and diagnosed promptly.

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