Retrospective study of the impact of unrecognised Kawasaki Disease, coronary aneurysm and ectasia
This is the first UK study to retrospectively review and characterise the angiographic prevalence of Kawasaki Disease. In doing so, both aneurysm and ectasia were observed with a relatively low frequency. However, their presence is associated with high-risk acute ischaemic presentations. A poor level of reporting of coronary abnormalities is reported and the authors advocate […]
Management of Kawasaki disease in adults
Kawasaki disease is the most common childhood vasculitis in the USA and the most common cause of acquired cardiac disease in children in developed countries.
NIHR Signal Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease
Early treatment with corticosteroids on top of standard therapy reduces the risk of serious heart problems in children under five with the rare vascular disease, Kawasaki disease.
Coronary Artery Complication in Kawasaki Disease and the Importance of Early Intervention
This systematic review and meta-analysis demonstrates that adjunctive corticosteroid therapy was associated with a significantly lower rate of coronary artery complication compared with intravenous immunoglobulin therapy, particularly among high-risk patients.
BPSU Surveillance of All Kawasaki Disease, UK & Ireland 2013-2015
Funded by KSSG UK, this research survey covered all children in the UK and Ireland who had a new diagnosis of KD between February 2013 and February 2015.
Cardiovascular status after Kawasaki Disease in the UK
This study examined circulating endothelial cells (CECs) years after KD. CECs were increased in patients with KD, were highest in those with CAA, but were also elevated in some patients without CAA, compatible with a state of persistent subclinical vasculitis years after the acute disease.