Kawasaki Disease Research Links

This study compared the safety and efficacy of warfarin plus aspirin versus aspirin alone for the treatment of children with giant coronary artery aneurysm (CAA) secondary to Kawasaki Disease, and concluded that warfarin plus aspirin therapy reduced the incidence of occlusion, cardiac infarction and death in children with giant CAA secondary to Kawasaki Disease.

This paper considers whether Kobayashi, Egami and Sano scores or application of up-to-date statistical methods (Random Forest) predict responses to standard IVIG therapy and the risk of persistent CAA in patients with KD in a mainly Caucasian population in Germany.

This is the first UK study to retrospectively review and characterise the angiographic prevalence of Kawasaki Disease.  In doing so, both aneurysm and ectasia were observed with a relatively low frequency. However, their presence is associated with high-risk acute ischaemic presentations. A poor level of reporting of coronary abnormalities is reported and the authors advocate […]

This guidance identifies risk factors, introduces the requirement for a person-specific protocol, and notes the need to ensure life-long follow up for those patients with coronary artery injury by a cardiology team with specialist interest in Kawasaki Disease.

This paper sets out the UK recommended guidance for patient management and clinical care for acute Kawasaki Disease and indicates long term care needs, together with summarising recent advances in the understanding of KD pathogenesis and therapeutics.

This study suggests that corticosteroids combined with IVIG as initial therapy for KD showed a more protective effect against CAA, compared with conventional IVIG therapy, and the efficacy was more pronounced in the high-risk patient group.

The prevalence of myopia has rapidly increased in recent decades and has led to a considerable global public health concern.

Kawasaki disease is the most common childhood vasculitis in the USA and the most common cause of acquired cardiac disease in children in developed countries.

Kawasaki disease (KD) is a pediatric vasculitis with coronary artery aneurysms (CAA) as its main complication.

Kawasaki disease is an acute vasculitis of childhood that leads to coronary artery aneurysms in ≈25% of untreated cases. It has been reported worldwide and is the leading cause of acquired heart disease in children in developed countries.