Kawasaki Disease

What is Kawasaki Disease?

Kawasaki Disease is a type of vasculitis. It mainly affects young children but it can affect people of any age – and its impact can be most serious in the very young, particularly infants.  Identified in 1967 in Japan by Dr Tomisaku Kawasaki, the cause of Kawasaki Disease is still unknown.  The illness presents with several symptoms common to a variety of other childhood diseases and infections and is therefore often misdiagnosed. Kawasaki Disease is a serious disease which if untreated can cause coronary artery damage. 

​Kawasaki Disease is the leading cause of acquired heart disease in children in the UK.

Symptoms of this “Red” Disease

Kawasaki Disease has a range of symptoms including a characteristic and distinctively persistent high fever for five days or more, rash, bloodshot eyes, “strawberry” tongue, cracked, dry lips, redness of the fingers and toes and swollen glands in the neck.  Kawasaki Disease can be present with some or all of these symptoms and symptoms often appear in series (i.e. not all at once). Incomplete Kawasaki Disease can be diagnosed with persistent fever plus two or more Kawasaki Disease symptoms.

Kawasaki Disease should always be considered in any child with unexplained persistent fever.  Kawasaki Disease is a serious illness.  It can cause coronary artery damage – damage to the blood vessels in the heart, and can lead to acquired heart disease in children.
Professor R Tulloh, Professor of Congenital Cardiology, Bristol Royal Hospital for Children​ and Societi Trustee​

Early Treatment is Key

Children affected by Kawasaki Disease have much improved chances of a good recovery with timely diagnosis and the correct treatment.​ Studies show that children treated early have a lower risk of serious heart damage than those treated later. Doctors should aim to diagnose and treat children as soon as possible – at five days of fever or as quickly as practical after that. The risk of heart damage increases proportionately with increasing delay.

Increasingly Common

Kawasaki Disease is increasingly common. Once thought of as a rare disease, this now outdated idea, wrongly held on to by some, leads to delayed diagnosis and with this, increased risk of serious heart damage for children. In the ten years to 2015, hospital admissions for Kawasaki Disease in England increased fourfold – and across the globe cases are doubling every ten years. This is why it is the leading cause of acquired heart disease in UK children.  We are working to raise awareness to make sure that doctors EXPECT to see Kawasaki Disease and are READY to treat it.