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Coronary Artery Complication in Kawasaki Disease and the Importance of Early Intervention

Shaojie Chen, MD, MM, PhD1,2; Ying Dong, MD, MM, PhD3; Marcio Galindo Kiuchi, MD, MS, PhD4; et al

December 2016

This systematic review and meta-analysis demonstrates that adjunctive corticosteroid t

herapy was associated with a significantly lower rate of coronary artery complication compared with intravenous immunoglobulin therapy, particularly among high-risk patients.

Meta-regression based on known variables demonstrated that the overall efficacy was negat

ively correlated with the duration of illness before corticosteroids therapy.

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