Acute management

AHA 2017 recommendations provide updated and best evidence-based guidance to healthcare providers who diagnose and manage Kawasaki disease, but clinical decision making should be individualized to specific patient circumstances.

This study suggests that early treatment with corticosteroids on top of standard therapy reduces the risk of serious heart problems in children under five with Kawasaki Disease.

An article on the diagnosis and treatment of Kawasaki Disease.

This systematic review and meta-analysis demonstrates that adjunctive corticosteroid therapy was associated with a significantly lower rate of coronary artery complication compared with intravenous immunoglobulin therapy, particularly among high-risk patients.

A paper evaluating the effect of corticosteroid therapy in KD.

This paper explores the acute dermatologic manifestations of Kawasaki Disease

This paper sets out the UK recommended guidance for patient management and clinical care for acute Kawasaki Disease and indicates long term care needs, together with summarising recent advances in the understanding of KD pathogenesis and therapeutics.

Abstract Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, affecting predominantly medium-sized arteries, particularly the coronary arteries. In developed countries KD is the commonest cause of acquired heart disease in childhood. The aetiology of KD remains unknown, and it is currently believed that one or more as yet unidentified infectious agents […]

Intravenous immunoglobulin plus corticosteroids prevent coronary artery abnormalities in Kawasaki disease

A case is reported of classical Kawasaki disease in an infant younger than 2 weeks of age. Echocardiography detected a coronary artery aneurysm on the fifth day of the illness. prompt treatment resulted in rapid improvement. Kawasaki Disease is not common in neonates, but it may follow a rapid and severe course.