Kawasaki Disease Increases the Incidence of Myopia

Yung-Jen Kung,1 Chang-Ching Wei,2,3 Liuh An Chen,4 Jiin Yi Chen,4 Ching-YaoChang,5 Chao-Jen Lin,6,7 Yun-Ping Lim,8 Peng-Tai Tien,2,9 Hsuan-Ju Chen,10Yong-San Huang,1 Hui-Ju Lin,4,9 and Lei Wan5,9,11,12

July 2017

The prevalence of myopia has rapidly increased in recent decades and has led to a considerable global public health concern.

In this study, we elucidate the relationship between Kawasaki Disease (KD) and the incidence of myopia. A total of 532 patients were included in the KD cohort and 2128 in the non-KD cohort. The risk of myopia (hazard ratio, 1.31; 95% confidence interval, 1.08–1.58; ) was higher among patients with KD than among those in the non-KD cohort.

The Cox proportional hazards regression model showed that irrespective of age, gender, and urbanization, Kawasaki Disease was an independent risk factor for myopia. Patients with Kawasaki Disease exhibited a substantially higher risk for developing myopia.